纳米科学与技术 生物医药纳米技术 方法与操作 英文版
作者： （美）赫斯特 主编
出版时间：2014年版
丛编项： 纳米科学与技术
内容简介
生物医学纳米技术：方法与操作一书涉及领域广泛，从实验室中纳米材料的概念到其临床应用，对生物医学纳米技术进行了总结。第一部分为实操篇，介绍合成各种溶液相及表面结合纳米材料的实用方法及其在传感、成像和/或医疗中的具体应用。第二部分介绍一系列实例，内容涉及纳米材料的毒理学，这些材料获美国食品药品监督管理局批准的常规途径，专利申请，市场营销，商业化及应用所涉及的法规与伦理学。
目录
Contents
Preface . v
Contributors ix
1 Biomedical Nanotechnology 1
Sarah J. Hurst
PART I USING NANOMATERIALS IN SENSING, IMAGING, AND THERAPEUTICS
2 Multiplexed Detection of Oligonucleotides with Biobarcoded Gold
Nanoparticle Probes 17
Jae-Seung Lee
3 Molecular Detection of Biomarkers and Cells Using Magnetic
Nanoparticles and Diagnostic Magnetic Resonance 33
Jered B. Haun, Tae-Jong Yoon, Hakho Lee, and Ralph Weissleder
4 Real-Time Quantum Dot Tracking of Single Proteins . 51
Jerry C. Chang and Sandra J. Rosenthal
5 Titanium Dioxide Nanoparticles in Advanced
Imaging and Nanotherapeutics 63
Tijana Rajh, Nada M. Dimitrijevic, and Elena A. Rozhkova
6 Surface Modification and Biomolecule Immobilization
on Polymer Spheres for Biosensing Applications 77
Chris R. Taitt, Lisa C. Shriver-Lake, George P. Anderson,
and Frances S. Ligler
7 Multivalent Conjugation of Peptides, Proteins, and DNA
to Semiconductor Quantum Dots . 95
Duane E. Prasuhn, Kimihiro Susumu, and Igor L. Medintz
8 A Single SnO2 Nanowire-Based Microelectrode 111
Jun Zhou, Yaguang Wei, Qin Kuang, and Zhong Lin Wang
9 Biosensing Using Nanoelectromechanical Systems 119
Ashish Yeri and Di Gao
10 Nano “Fly Paper” Technology for the Capture of Circulating Tumor Cells 141
Shutao Wang, Gwen E. Owens, and Hsian-Rong Tseng
11 Polymeric Nanoparticles for Photodynamic Therapy 151
Yong-Eun Koo Lee and Raoul Kopelman
12 Hydrogel Templates for the Fabrication of Homogeneous
Polymer Microparticles 179
Ghanashyam Acharya, Matthew McDermott, Soo Jung Shin,
Haesun Park, and Kinam Park
13 Antibacterial Application of Engineered Bacteriophage
Nanomedicines: Antibody-Targeted, Chloramphenicol Prodrug
Loaded Bacteriophages for Inhibiting the Growth
of Staphylococcus aureus Bacteria 187
Lilach Vaks and Itai Benhar
14 Viruses as Nanomaterials for Drug Delivery 207
Dustin Lockney, Stefan Franzen, and Steven Lommel
15 Applications of Carbon Nanotubes in Biomedical Studies . 223
Hongwei Liao, Bhavna Paratala, Balaji Sitharaman,
and Yuhuang Wang
16 Electrospun Nanofibrous Scaffolds for Engineering Soft Connective Tissues 243
Roshan James, Udaya S. Toti, Cato T. Laurencin,
and Sangamesh G. Kumbar
17 Peptide Amphiphiles and Porous Biodegradable Scaffolds
for Tissue Regeneration in the Brain and Spinal Cord . 259
Rutledge G. Ellis-Behnke and Gerald E. Schneider
18 Computational Simulations of the Interaction of Lipid Membranes
with DNA-Functionalized Gold Nanoparticles 283
One-Sun Lee and George C. Schatz
PART II TRANSLATING NANOSCIENCE AND TECHNOLOGY
FROM THE LAB TO THE CLINIC
19 Cytotoxic Assessment of Carbon Nanotube Interaction
with Cell Cultures . 299
Hanene Ali-Boucetta, Khuloud T. Al-Jamal,
and Kostas Kostarelos
20 Nanoparticle Toxicology: Measurements of Pulmonary
Hazard Effects Following Exposures to Nanoparticles . 313
Christie M. Sayes, Kenneth L. Reed, and David B. Warheit
21 Nanoparticle Therapeutics: FDA Approval, Clinical Trials,
Regulatory Pathways, and Case Study . 325
Aaron C. Eifler and C. Shad Thaxton
22 Legislating the Laboratory? Promotion and Precaution
in a Nanomaterials Company . 339
Robin Phelps and Erik Fisher
23 Navigating the Patent Landscapes for Nanotechnology: English
Gardens or Tangled Grounds? 359
Douglas J. Sylvester and Diana M. Bowman
24 Scientific Entrepreneurship in the Materials and Life Science Industries 379
Jose Amado Dinglasan, Darren J. Anderson, and Keith Thomas
25 Applying the Marketing Mix (5 Ps) to Bionanotechnology 393
Michael S. Tomczyk
26 Managing the “Known Unknowns”: Theranostic Cancer
Nanomedicine and Informed Consent 413
Fabrice Jotterand and Archie A. Alexander
Index 431
